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Jane B Trepel Selected Research

Estrogen Receptors

1/2016The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat.
6/2013Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor.

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Jane B Trepel Research Topics

Disease

69Neoplasms (Cancer)
01/2024 - 01/2002
17Prostatic Neoplasms (Prostate Cancer)
01/2021 - 03/2003
12Carcinoma (Carcinomatosis)
03/2024 - 03/2003
12Breast Neoplasms (Breast Cancer)
10/2023 - 01/2002
9Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2021 - 01/2016
7Disease Progression
01/2022 - 02/2014
6Ovarian Neoplasms (Ovarian Cancer)
03/2024 - 01/2015
5Lung Neoplasms (Lung Cancer)
07/2021 - 03/2005
4Adenocarcinoma
01/2024 - 03/2005
4Triple Negative Breast Neoplasms
10/2023 - 01/2018
4Leukemia
11/2021 - 09/2002
4Circulating Neoplastic Cells
01/2021 - 04/2016
4Neoplasm Metastasis (Metastasis)
01/2021 - 07/2007
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2021 - 08/2002
3Neutropenia
12/2020 - 11/2014
3Diarrhea
12/2020 - 11/2011
3Urinary Bladder Neoplasms (Bladder Cancer)
05/2017 - 11/2015
3Lymphoma (Lymphomas)
01/2017 - 06/2005
3Carcinogenesis
08/2015 - 03/2003
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 09/2008
2Nausea
12/2020 - 11/2014
2Fatigue
12/2020 - 10/2005
2Thrombocytopenia (Thrombopenia)
12/2020 - 11/2014
2Glioma (Gliomas)
01/2020 - 01/2004
2Renal Cell Carcinoma (Grawitz Tumor)
12/2019 - 04/2013
2Thymoma (Thymic Carcinoma)
02/2015 - 02/2014
2Pheochromocytoma
04/2013 - 01/2013
2Hematologic Neoplasms (Hematological Malignancy)
05/2008 - 08/2002
2Myeloid Leukemia (Leukemia, Myelocytic)
04/2007 - 08/2002
1Cystadenocarcinoma
01/2024

Drug/Important Bio-Agent (IBA)

18Histone Deacetylase InhibitorsIBA
01/2023 - 01/2004
15Proteins (Proteins, Gene)FDA Link
07/2021 - 01/2005
14Biomarkers (Surrogate Marker)IBA
01/2023 - 01/2015
14entinostat (MS 275)IBA
01/2023 - 02/2002
12PlatinumIBA
03/2024 - 01/2015
8Immune Checkpoint InhibitorsIBA
01/2022 - 11/2015
7Phosphotransferases (Kinase)IBA
12/2020 - 05/2008
6AntigensIBA
07/2021 - 01/2005
6RRx-001IBA
02/2021 - 01/2016
6Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2017 - 07/2011
5Androgen Receptors (Androgen Receptor)IBA
01/2018 - 07/2011
5STA 9090IBA
01/2017 - 12/2010
4prexasertibIBA
03/2024 - 01/2018
4exemestane (Aromasin)FDA Link
01/2023 - 06/2013
4cabozantinibIBA
01/2022 - 01/2020
4Messenger RNA (mRNA)IBA
01/2020 - 06/2004
4Cisplatin (Platino)FDA LinkGeneric
01/2018 - 11/2014
4belinostatIBA
01/2018 - 11/2014
4Molecular Chaperones (Chaperone, Molecular)IBA
02/2016 - 06/2013
3Immunotoxins (Immunotoxin)IBA
01/2024 - 01/2020
3Hormones (Hormone)IBA
10/2023 - 10/2021
3EnzymesIBA
12/2021 - 12/2019
3Aromatase InhibitorsIBA
10/2021 - 06/2013
3VaccinesIBA
07/2021 - 08/2016
3Docetaxel (Taxotere)FDA Link
01/2021 - 04/2010
3B7-H1 AntigenIBA
01/2021 - 11/2015
3Prednisone (Sone)FDA LinkGeneric
01/2021 - 04/2010
3(2,4- dihydroxy- 5- isopropylphenyl)- (5- (4- methylpiperazin- 1- ylmethyl)- 1,3- dihydroisoindol- 2- yl)methanoneIBA
12/2020 - 08/2015
3Peptides (Polypeptides)IBA
11/2019 - 08/2016
3Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2019 - 07/2015
3Etoposide (VP 16)FDA LinkGeneric
01/2019 - 04/2016
3olaparibIBA
01/2019 - 01/2015
3romidepsin (FK228)FDA Link
01/2018 - 03/2005
3Histone Deacetylases (Histone Deacetylase)IBA
01/2018 - 02/2002
3AndrogensIBA
01/2017 - 10/2005
3DepsipeptidesIBA
09/2008 - 03/2004
3beta CateninIBA
05/2008 - 08/2002
2AntibodiesIBA
01/2024 - 12/2018
2MesothelinIBA
01/2024 - 01/2020
2LMB-100IBA
01/2024 - 01/2020
2LigandsIBA
10/2023 - 01/2018
2NivolumabIBA
01/2022 - 11/2020
2Lenalidomide (CC 5013)FDA Link
11/2021 - 10/2016
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2021 - 11/2014
2Lactic Acid (Lactate)FDA LinkGeneric
11/2020 - 01/2020
2InterferonsIBA
01/2020 - 05/2009
2cediranib (AZD2171)IBA
01/2019 - 01/2015
2Protein Isoforms (Isoforms)IBA
01/2019 - 06/2013
2durvalumabIBA
01/2019 - 12/2018
2Oncogene Proteins (Oncogene Protein)IBA
12/2018 - 10/2012
2TARPIBA
12/2018 - 08/2016
2DNA (Deoxyribonucleic Acid)IBA
01/2018 - 03/2005
2Topotecan (Hycamtin)FDA LinkGeneric
01/2018 - 01/2018
2Androgen Antagonists (Antiandrogens)IBA
01/2018 - 11/2013
2EndoglinIBA
01/2017 - 10/2015
2carotuximabIBA
01/2017 - 10/2015
2Antineoplastic Agents (Antineoplastics)IBA
01/2017 - 01/2002
2Bevacizumab (Avastin)FDA Link
10/2016 - 04/2010
2Estrogen ReceptorsIBA
01/2016 - 06/2013
2Tyrosine (L-Tyrosine)FDA Link
08/2015 - 05/2008
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2014 - 12/2004
2tanespimycin (17AAG)IBA
01/2013 - 12/2010
2Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
06/2004 - 01/2002
1tofacitinibIBA
01/2024
1ExotoxinsIBA
01/2024

Therapy/Procedure

27Therapeutics
11/2023 - 03/2003
7Immunotherapy
11/2021 - 11/2015
7Drug Therapy (Chemotherapy)
02/2021 - 02/2015
7Castration
01/2021 - 04/2010
2Aftercare (After-Treatment)
01/2020 - 12/2018